Continental shelves are productive ecosystems which provide key ecosystem services such as carbon storage or climate change mitigation. Among these services, benthic communities play an essential vital role (e.g. bioturbation, nutrient cycling, productivity, ...). Ecosystem services can be impaired when benthic communities are disturbed by pressures generated by human activities such as bottom trawling. In order to evaluate the resilience of the seafloor of continental shelves under fishing pressure, it is necessary to assess the taxonomic and functional diversities of its benthic communities and their sensitivity to this pressure. This can allow to understand how the resilience is spatially structured according to natural and fishing forcings. Our study focuses on the epi-benthic mega-invertebrates of the continental shelf of the Bay of Biscay (NE-Atlantic). We test the stability and resilience of the ecosystems according to fishing intensity gradients and spatially from “benthic seascapes” previously delineated. To do this, we analyse the taxonomic and functional diversities of the benthic communities in relation to environmental and anthropogenic forcings. Moreover, we use benthic communities indicators to trawling pressure already developed. Results put forward coast-to-offshore variability in resilience and stability. The role played by environmental and bottom trawling (as an anthropogenic forcing) on the seafloor is discussed.